Synthesis and DNA strand breakage activity of some 1,4-diazepines.
نویسندگان
چکیده
Reactions of 1,3-propanediamine with alpha-dicarbonyl compounds (1a-e) were examined and various condensed heterocyclic compounds such as 1,4-diazepines (2) and 3-pyrimidine derivatives (3) were obtained. Some of 1,4-diazepines (2) showed DNA strand breakage activity.
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ورودعنوان ژورنال:
- Chemical & pharmaceutical bulletin
دوره 51 1 شماره
صفحات -
تاریخ انتشار 2003